Expanded Disability Status Scale (EDSS) 0 - Normal neurological exam (all Functional Systems [FS] grade 0) 1.0 - No disability, minimal signs in one FS (one FS grade 1) 1.5 - No disability, minimal signs in more than one FS (more than one FS grade 1) 2.0 - Minimal disability in one FS (one FS grade 2, others 0 or 1) 2.5 - Minimal disability in two FS (two FS grades 2, others 0 or 1) 3.0 - Moderate disability in one FS (one FS grade 3, others 0 or 1) though fully ambulatory; or mild disability in three or four FS (three/four FS grades 2, others 0 or 1) though fully ambulatory 3.5 - Fully ambulatory but with moderate disability in one FS (one FS grade 3) and mild disability in one or two FS (one/two FS grade 2) and others 0 or 1; or fully ambulatory with two FS grades 3 (others 0 or 1); or fully ambulatory with five FS grades 2 (others 0 or 1) 4.0 - Unable to walk > 25 feet without aid 4.5 - Unable to walk > 100 feet without aid 5.0 - Relies on a walking aid; unable to walk > 300 feet without resting 5.5 - Relies on a walking aid; unable to walk > 200 feet without resting 6.0 - Unable to walk more than 50 feet with or without aid; cannot stand unaided for five minutes 6.5 - Unable to walk more than 10 feet with or without aid; cannot stand unaided for two minutes 7.0 - Unable to walk 5 meters even with aid, essentially restricted to wheelchair; wheels self and transfers alone; up and about in wheelchair some 12 hours a day 7.5 - Unable to take more than a few steps; restricted to wheelchair; may need some help in transferring and in wheeling self 8.0 - Essentially restricted to bed or chair or perambulated in wheelchair, but out of bed most of the day; retains many self-care functions; generally has effective use of arms 8.5 - Essentially restricted to bed much of the day; has some effective use of arm(s); retains some self-care functions 9.0 - Helpless bed patient; can communicate and eat 9.5 - Totally helpless bed patient; unable to communicate effectively or eat/swallow 10 - Death due to MS